Drug Analyses in Meconium

Drug abuse during pregnancy poses a serious threat to the normal development of the foetus. As the number of cases have been increased recently, it becomes more important to treat new-borns as quickly as possible. Meconium, the first stool after birth, can be used to detect a possible drug abuse of the mother during the 2nd and 3rd trimester reliably.

Using liquid chromatography (LC-MS/MS) the following drugs can be quantified:

  • Amphetamines/Methamphetamines
  • Benzodiazepines (incl. Z-Drugs)
  • Cannabinoids
  • Cocaine
  • Ketamine
  • Methadone
  • Opiates
  • Opioids

NOTE: Please send meconium samples immediately after collection to the lab. Drugs are stable in frozen samples (-15 °C) for up to nine months.

Further information on relevant topics

MPA Fitness to Drive

MPA Fitness to Drive

In most industrial countries if a driver loses his driving license as a result of drug or alcohol offense he has to prove abstinence for several months up to one year. The exact conditions of drug testing in urine or hair are different from country to country and depend on the individual situation.

Blood

Blood

Blood, serum or plasma are the matrices of choice for toxicological analyses if the objective is to assess the acute impact of a drug of abuse on a person.

Dried Blood Samples

Dried Blood Samples

Chromatographic drug analyses (LC-MS/MS) in capillary blood and DBS (dried blood samples) respectively are of increasing importance.

Urine

Urine

For many years, urine has been the preferred specimen for drug of abuse testing. Depending on the substance or metabolite tested, the type of consumption (smoking, sniffing, injection), the dose and the frequency of consumption, drugs can be measured for several days or weeks. Samples then are collected under direct supervision to minimize manipulation attempts.

Hair

Hair

In the last few years hair testing for drugs has been rapidly gaining recognition. During hair growth (about 1 cm per month for head hair) drugs of abuse and their metabolites are continuously incorporated and deposited into the hair matrix following consumption of alcohol or drugs.

Saliva

Saliva

The testing of drugs in saliva is a rather new alternative to the analysis of drugs in blood or urine. Particularly in workplace drug testing, a sample can be collected without medical intervention to prove or exclude exposure to drugs of abuse.

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