Fitness to Drive - MPA (Medical Psychological Assessment)

Laboratory Krone has a forensic accreditation according to DIN EN ISO/IEC 17025 for testing of alcohol and drugs in urine, blood, hair and oral fluid. Moreover we are accredited for the interpretation of forensic toxicological results.
The drug screening in urine in the context of driving license re-granting includes the testing of the following substances:

Tests in urine

Screening for drugs of abuse

  • Opiates (morphine, 6-monoacetylmorphine, codeine and dihydrocodeine)
  • Cocaine (including metabolites)
  • Amphetamine and methamphetamine (incl. MDMA, MDA and MDEA)
  • Cannabinoids
  • Methadone (incl. EDDP)
  • Benzodiazepines.

Screening for drugs of abuse plus opioids

Same as screening for drugs of abuse in urine plus opioids (buprenorphine, tilidine, tramadol and their metabolites)

Screening for drugs of abuse plus medical drugs

Same as screening for drugs of abuse in urine plus medical drugs

Ethylglucuronide (EtG)

Ethylglucuronide in urine is screened with an immunoassay (cut-off at 0.1 mg/L). A positive result is verified with a confirmation technique such as GC-MS or LC-MS/MS (cut-off at 0.1 mg/L).

Tests in hair

Screening for drugs of abuse

  • Opiates (morphine, 6-monoacetylmorphine, codeine and dihydrocodeine)
  • Cocaine (including metabolites)
  • Amphetamine and methamphetamine (incl. MDMA, MDA and MDEA)
  • Cannabinoids
  • Methadone (incl. EDDP)
  • Benzodiazepines.

Screening for drugs of abuse plus opioids

Same as screening for drugs of abuse in hair plus opioids (buprenorphine, tilidine, tramadol and their metabolites)

Screening for drugs of abuse plus medical drugs

Same as screening for drugs of abuse in hair plus medical drugs

Ethylglucuronide (ETG)

Ethylglucuronide in hair is measured with GC-MS/MS or LC-MS/MS.

 

Remark

Urine and hair samples are stored for a minium of 18 months.

 

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Further information on relevant topics

Ethylglucuronide in Urine

Ethylglucuronide in Urine

Ethylglucuronide (EtG) is produced in the liver and is a direct metabolite of the alcohol consumed. It is progressively eliminated in urine and depending on the amount of alcohol taken ethylglucuronide can be detected for 12-48 hrs. EtG in urine is a short-term marker of alcohol consumption and can be used to demonstrate abstinence during the last 1 to 2 days.

Ethylglucuronide in Hair

Ethylglucuronide in Hair

The major part of ethylglucuronide (EtG) produced in the liver as a metabolite of alcohol is eliminated in urine. A small fraction is incorporated into the hair matrix. That way hair samples can be analyzed for EtG.

Drug Tests in Urine

Drug Tests in Urine

For many years, urine has been the preferred specimen for drug of abuse testing. Depending on the substance or metabolite tested, the type of consumption (smoking, sniffing, injection), the dose and the frequency of consumption, drugs can be measured for several days or weeks. Samples then are collected under direct supervision to minimize manipulation attempts.

Drug Tests in Hair

Drug Tests in Hair

In the last few years hair testing for drugs has been rapidly gaining recognition. During hair growth (about 1 cm per month for head hair) drugs of abuse and their metabolites are continuously incorporated and deposited into the hair matrix following consumption of alcohol or drugs.

ILAC-MRA
DAKKS
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